{"id":85,"date":"2021-10-05T09:20:18","date_gmt":"2021-10-05T00:20:18","guid":{"rendered":"https:\/\/wp.pharm.kitasato-u.ac.jp\/yakubutsu4\/?page_id=85"},"modified":"2021-10-05T11:22:40","modified_gmt":"2021-10-05T02:22:40","slug":"research-achievements","status":"publish","type":"page","link":"https:\/\/wp.pharm.kitasato-u.ac.jp\/yakubutsu4\/en\/research-achievements","title":{"rendered":"Research achievements"},"content":{"rendered":"

2021<\/strong><\/h1>\n

Megumi Shiomi, Momoka Kurobuchi, Yoichi Tanaka, Tesshu Takada, Katsuya Otori.\u00a0Pill Counting in the Determination of Factors Affecting Medication Adherence in Patients with Type 2 Diabetes: A Retrospective Observational Study.\u00a0Diabetes therapy: research, treatment and education of diabetes and related disorders 12(7) 1993-2005<\/p>\n

 <\/p>\n

Wataru Ando, Takeshi Horii, Takayuki Uematsu, Hideaki Hanaki, Koichiro Atsuda, Katsuya Otori.\u00a0Impact of overlapping risks of type 2 diabetes and obesity on coronavirus disease severity in the United States. Scientific reports 11(1) 17968-17968<\/p>\n

 <\/p>\n

Hiroaki Yokomori, Wataru Ando, Masaya Oda. Plasmalemmal Vesicle-Associated Protein Is Associated with Endothelial Cells Sprouting from the Peribiliary Capillary Plexus in Human Cirrhotic Liver.\u00a0Journal of vascular research 1-9<\/p>\n

 <\/p>\n

Manahito Aoki, Midori Naya, Shiho Arima, Kaori Shinohara, Masahiro Kato, Kiyoshi Shibuya, Masaki Ohtawa, Tohru Nagamitsu, Katsuya Otori. Mixture of clopidogrel bisulfate and magnesium oxide tablets reduces clopidogrel dose administered through a feeding tube.\u00a0Journal of Pharmaceutical Health Care and Sciences 7(1)<\/p>\n

 <\/p>\n

\u5869\u898b\u3081\u3050\u307f, \u7530\u4e2d\u5eb8\u4e00, \u5c3e\u9ce5\u52dd\u4e5f.\u00a0\u85ac\u5b66\u5b9f\u52d9\u5b9f\u7fd2\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3092\u57fa\u306b\u8003\u6848\u3057\u305f\u75c5\u9662\u5b9f\u7fd2\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u8a55\u4fa1.\u00a0\u85ac\u5b66\u6559\u80b2 5 2021\u5e749\u6708<\/p>\n

 <\/p>\n

\u5a66\u5ddd\u8cb4\u535a, \u51a8\u6fa4\u6df3, \u690e\u5d07, \u4f50\u3005\u6728\u5584\u4fe1, \u65b0\u4e95\u4e07\u7406\u5b50, \u5409\u7530\u5c1a\u7f8e, \u677e\u539f\u8087, \u6a2a\u7530\u8a13\u7537, \u5c3e\u9ce5\u52dd\u4e5f, \u539a\u7530\u5e78\u4e00\u90ce.\u00a0\u75c5\u9662\u85ac\u5264\u5e2b\u306e\u30c8\u30ec\u30fc\u30b7\u30f3\u30b0\u30ec\u30dd\u30fc\u30c8\u6d3b\u7528\u306b\u95a2\u3059\u308b\u610f\u8b58\u8abf\u67fb\uff5e\u30c8\u30ec\u30fc\u30b7\u30f3\u30b0\u30ec\u30dd\u30fc\u30c8\u306e\u6d3b\u7528\u63a8\u9032\u306b\u5411\u3051\u3066\uff5e.\u00a0\u65e5\u672c\u85ac\u5264\u5e2b\u4f1a\u96d1\u8a8c 73(8) 837-841 2021\u5e748\u6708<\/p>\n

\u00a0<\/strong><\/p>\n

2020<\/strong><\/h1>\n

\u83c5\u91ce\u96c4\u592a, \u5411\u4e95\u6f64\u4e00, \u938c\u7530\u88d5\u4ecb, \u83c5\u539f\u5927\u8f14, \u4e45\u4fdd\u7530\u7406\u6075, \u5c3e\u9ce5\u52dd\u4e5f, \u9ad8\u5ca9\u5fb9\u5e78.\u00a0\u611f\u67d3\u75c7\u306b\u4f34\u3046\u64ad\u7a2e\u6027\u8840\u7ba1\u5185\u51dd\u56fa\u75c7\u5019\u7fa4\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u7d44\u63db\u3048\u30c8\u30ed\u30f3\u30dc\u30e2\u30c7\u30e5\u30ea\u30f3\u30a2\u30eb\u30d5\u30a1\u88fd\u5264\u306e\u6295\u4e0e\u65e5\u6570\u306b\u95a2\u3059\u308b\u5f8c\u65b9\u8996\u7684\u691c\u8a0e.\u00a0\u533b\u7642\u85ac\u5b66 47(1) 43-53 2021\u5e741\u6708<\/p>\n

 <\/p>\n

Isao Okazaki, Shinsuke Shibata, Wataru Ando, Takayo Yanagawa, Hiroaki Yokomori, Akira Sonoda, Norihiko Suzuki, Eigoro Yamanouchi, Shinya Okada, Shinichi Kamikura, Kazuaki Hachimura, Takashi Takaki, Katsuya Otori, Yutaka Suzuki, Hideyuki Okano, Yutaka Inagaki.\u00a0Sequential Matrix Metalloproteinase-1 Expression Triggered by Infiltrating Monocytic Lineage Cells Modulates Pathophysiological Aspects of Human Nonalcoholic Steatohepatitis.\u00a0Metalloproteinases In Medicine 7(1) 1-13<\/p>\n

 <\/p>\n

Hiroaki Yokomori, Wataru Ando.\u00a0Spatial expression of glucagon-like peptide 1 receptor and caveolin-1 in hepatocytes with macrovesicular steatosis in non-alcoholic steatohepatitis.\u00a0BMJ open gastroenterology 7(1)<\/p>\n

 <\/p>\n

Manahito Aoki, Satsuki Oda, Satoshi Kubota, Sakae Saito, Norio Yokota, Atsushi Shibazaki, Kiyoshi Shibuya, Magoichi Sako, Katsuya Otori.<\/p>\n

Safe Handling Method for Splitting Azathioprine Tablets.\u00a0Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 141(1) 125-133<\/p>\n

 <\/p>\n

Megumi Shiomi, Yoichi Tanaka, Tesshu Takada, Katsuya Otori.\u00a0Determining whether the effect of liraglutide on non\u2010alcoholic fatty liver disease depends on reductions in the body mass index.\u00a0JGH open (4) 995-1001<\/p>\n

\u00a0<\/strong><\/p>\n

2019<\/strong><\/h1>\n

Wataru Ando, Yumika Imamura, Hideyuki Nagashima, Kouji Kondo, Kazunori Nakamura, Katsuya Otori.\u00a0Handling and packaging of medical bags at acute disaster sites under high-temperature conditions.\u00a0BMC research notes 13(1) 158-158<\/p>\n

\u00a0<\/strong><\/p>\n

Ando W, Kikuchi K, Uematsu T, Yokomori H, Takaki T, Sogabe M, Kohgo Y, Otori K, Ishikawa S, Okazaki I. Novel breast cancer screening: combined expression of miR-21 and MMP-1 in urinary exosomes detects 95% of breast cancer without metastasis. Sci Rep.<\/strong><\/em>2019 Sep 19;9(1):13595<\/p>\n

 <\/p>\n

Tanaka Y, Inoue A, Mizunuma T, Matsumura H, Yokomori H, Komiyama T, Otori K. Tolerability of erythrocyte ribavirin triphosphate concentrations depends on the ITPA genotype. Ther Drug Monit 2019 Aug; 41\/ 4, 497-502.<\/p>\n

 <\/p>\n

Aoki M, Hamasaki Y, Naya M, Shishikura H, Kato M, Shibuya K, Aoyagi M, Otori K. Evaluation of Measures against Exposure during Administration of Hazardous Drugs through a Feeding Tube. Biol. Pharm. Bull.2019 Nov;42(11), 1823-1829.<\/p>\n

 <\/p>\n

2018<\/strong><\/h1>\n

 <\/p>\n

Shiomi M, Takada T, Tanaka Y, Yajima K, Isomoto A, Sakamoto M, Otori K. Clinical factors associated with the occurrence of nausea and vomiting in type 2 diabetic patients treated with glucagon-like peptide-1 receptor agonists. J Diabetes Investig 2019 Mar;10(2), 408-417<\/p>\n

 <\/p>\n

\u9752\u6728\u5b66\u4e00\uff0c\u4e45\u4fdd\u7530\u8061\uff0c\u4eca\u91ce\u53cb\u8cb4\uff0c\u5927\u548c\u7530\u771f\u672a\uff0c\u5c0f\u7530\u3055\u3064\u304d\uff0c\u6a2a\u7530\u8a13\u7537\uff0c\u67f4\ufa11\u3000\u6df3\uff0c\u6e0b\u8c37\u3000\u6e05\uff0c\u5c3e\u9ce5\u52dd\u4e5f. \u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u9320\u304a\u3088\u3073\u30b7\u30af\u30ed\u30db\u30b9\u30d5\u30a1\u30df\u30c9\u9320\u306e\u7c89\u7815\u8abf\u5264\u306b\u304a\u3051\u308b\u5206\u5305\u6a5f\u306e\u6c5a\u67d3\u9664\u53bb\u306b\u52b9\u679c\u7684\u306a\u6e05\u6383\u6cd5\u306e\u691c\u8a0e. \u65e5\u672c\u75c5\u9662\u85ac\u5264\u5e2b\u4f1a\u96d1\u8a8c 2019 Mar;55(3), 273-278.<\/p>\n

 <\/p>\n

Yokomori H, Ando W, Oda M. Cavin-1 is linked to lipid droplet formation in human hepatic stellate cells. Med Mol Morphol<\/em><\/strong>.<\/em> 2019 Mar 15. doi: 10.1007\/s00795-019-00219-4. [Epub ahead of print]<\/p>\n

 <\/p>\n

Yokomori H, Ando W, Oda M. Caveolin-1 is related to lipid droplet formation in hepatic stellate cells in human liver. Acta Histochemica<\/em><\/strong> 2019 Feb; 121:113-118.<\/p>\n

\u00a0<\/strong>\u00a0<\/strong><\/p>\n

Yang JJ, Whirl\u2010Carrillo M, Scott SA, Turner AJ, Schwab M, Tanaka Y, Suarez\u2010Kurtz G, Schaeffeler E, Klein TE, Miller NA, Gaedigk A.\u00a0Pharmacogene Variation Consortium Gene Introduction: NUDT15.\u00a0Clin Pharmacol Ther. 2018 [Epub ahead of print]<\/p>\n

 <\/p>\n

Yokomori H, Ando W, Kaneko K, Suzuki H, Igarashi K, Oda M.\u00a0Autotaxin and vascular endothelial growth factor receptor-2 and -3 relate vascular development in chronic viral hepatitis C progression.\u00a0APMIS 2018 Nov; 126:913-921<\/p>\n

 <\/p>\n

Kondo Y, Fukuyama T, Yamamura R, Futawatari N, Ichiki Y, Tanaka Y, Nishi Y, Takahashi Y, Yamazaki H, Kobayashi N, Watanabe M.\u00a0Detection of KK-LC-1 Protein, a Cancer\/Testis Antigen, in Patients with Breast Cancer.\u00a0Anticancer Research. 2018 Oct; 38(10):5923-5928<\/p>\n

 <\/p>\n

Tanaka Y, Yokomori H, Otori K.\u00a0Induction of inosine triphosphatase activity during ribavirin treatment for chronic hepatitis C.\u00a0Clin Chim Acta 2018 Jul; 482:16-20<\/p>\n

 <\/p>\n

Ando W, Yokomori H, Kaneko F, Kaneko M, Igarashi K, Suzuki H.\u00a0Serum Autotaxin Concentrations Reflect Changes in Liver Stiffness and Fibrosis following Antiviral Therapy in a Patient with Chronic Hepatitis C.\u00a0Hepatology Communications 2018 Sep; 2(9):1111-1122<\/p>\n

 <\/p>\n

Shiomi M, Takada T, Tanaka Y, Yajima K, Isomoto A, Sakamoto M, Otori K.\u00a0Clinical factors associated with the occurrence of nausea and vomiting in type 2 diabetic patients treated with glucagon-like peptide-1 receptor agonists.\u00a0J Diabetes Investig. 2018 Jul 23. [Epub ahead of print]<\/p>\n

 <\/p>\n

Kubota R, Shibuya K, Tanaka Y, Aoki M, Shiomi M, Ando W, Otori K, Komiyama T.\u00a0Clinical Pharmacy Education in Japan: Using Simulated Patients in Laboratory-Based Communication-Skills Training before Clinical Practice. Pharmacy (Basel). 2018 Jun 1;6(2). pii: E49<\/p>\n

 <\/p>\n

Tanaka Y, Yokomori H, Otori K.\u00a0Induction of inosine triphosphatase activity during ribavirin treatment for chronic hepatitis C.\u00a0Clin Chim Acta. 2018 Jul;482:16-20<\/p>\n

 <\/p>\n

Ando W, Yokomori H, Tsutsui N, Yamanouchi E, Suzuki Y, Oda M, Inagaki Y, Otori K, Okazaki I. Serum Matrix Metalloproteinase-1 Level Represents Disease Activity as Opposed to Fibrosis in Patients with Histologically Proven Nonalcoholic Steatohepatitis. Clin Mol Hepato. 2018 Mar;24(1):61-76<\/p>\n

 <\/p>\n

Huang M, Inukai T, Miyake K, Tanaka Y, Kagami K, Abe M, Goto H, Minegishi M, Iwamoto S, Sugihara E, Watanabe A, Somazu S, Shinohara T, Oshiro H, Akahane K, Goi K, Sugita K.\u00a0Clofarabine exerts antileukemic activity against cytarabine-resistant B-cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression. Cancer Med. 2018 Apr;7(4):1297-1316<\/p>\n

 <\/p>\n

Urayama KY, Takagi M, Kawaguchi T, Matsuo K, Tanaka Y, Ayukawa Y, Arakawa Y, Hasegawa D, Yuza Y, Kaneko T, Noguchi Y, Taneyama Y, Ota S, Inukai T, Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa Y, Kurosawa H, Nakamura K, Moriwaki K, Goto H, Sekinaka Y, Morita D, Kato M, Takita J, Tanaka T, Inazawa J, Koh K, Ishida Y, Ohara A, Mizutani S, Matsuda F, Manabe A.\u00a0Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese. Sci Rep. 2018; 8\/ 1, 789<\/p>\n

 <\/p>\n

 <\/p>\n

2017<\/strong><\/h1>\n

 <\/p>\n

Tokumoto M,Shibuya K, Jin-Yong Lee, Tohyama C, Satoh M, Effect of metallothionein on ethanol-induced hepatotoxicity in mice. Fundam Toxicol Sci\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 . 2017;4(6):269-273<\/p>\n

 <\/p>\n

\u7530\u4e2d\u3000\u5eb8\u4e00. \u65e5\u672c\u4eba\u5c0f\u5150\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u306b\u304a\u3051\u308bNUDT15\u3068ABCC4\u907a\u4f1d\u5b50\u591a\u578b\u306e6-\u30e1\u30eb\u30ab\u30d7\u30c8\u30d7\u30ea\u30f3\u611f\u53d7\u6027\u3078\u306e\u5f71\u97ff. \u81e8\u5e8a\u8840\u6db2. 2017;58(8):950-956<\/p>\n

 <\/p>\n

Ando W, Yokomori H, Otori K, Oda M. The Apelin Receptor APJ in Hematopoietic Stem Cells\/Progenitor Cells in the Early Stage of Non-Alcoholic Steatohepatitis. J Clin Med Res. 2017;9(9):809-811<\/p>\n

 <\/p>\n

Yokomori H, Oda M, Ando W, Inagaki Y, Okazaki I. Hepatic progenitor cell expansion in early-stage nonalcoholic steatohepatitis: evidence from immunohistochemistry and immunoelectron microscopy of matrix metalloproteinase-1. Med Mol Morphol. 2017\/06<\/p>\n

 <\/p>\n

Tanaka Y, Nakadate H, Kondoh K, Koh K, Manabe A. Interaction between NUDT15 and ABCC4 variants enhances intolerability of 6-mercaptopurine in Japanese patients with childhood acute lymphoblastic leukemia. Pharmacogenomics Journal<\/em>. 2017\/04<\/p>\n

 <\/p>\n

\u5869\u898b\u3081\u3050\u307f, \u7530\u4e2d\u5eb8\u4e00, \u5742\u672c\u5c06\u898f, \u78ef\u5143\u6643, \u4e2d\u6751\u9ebb\u7f8e, \u9ad8\u7530\u54f2\u79c0, \u5c0f\u5bae\u5c71\u8cb4\u5b50. \u30ea\u30e9\u30b0\u30eb\u30c1\u30c9\u306e\u6cbb\u7642\u52b9\u679c\u8a55\u4fa1\u6642\u671f\u304a\u3088\u3073\u8840\u7cd6\u6539\u5584\u52b9\u679c\u306e\u4e88\u6e2c\u56e0\u5b50\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7cd6\u5c3f\u75c5<\/em>. 2017; 60(5):361-369.<\/p>\n

 <\/p>\n

\u4e45\u4fdd\u7530\u7406\u6075\uff0c\u77f3\u5ddd\u4e9c\u91cc\u6c99\uff0c\u5c3e\u9ce5\u52dd\u4e5f.\u3000\u4e8c\u6b21\u6551\u6025\u75c5\u9662\u306e\u6551\u6025\u30bb\u30f3\u30bf\u30fc\u306b\u304a\u3051\u308b\u533b\u85ac\u54c1\u306e\u4f7f\u7528\u5b9f\u614b\u3068\u9069\u6b63\u4f7f\u7528\u306b\u5411\u3051\u3066\u306e\u8a55\u4fa1.\u3000\u85ac\u4e8b\u65b0\u5831. 2017;2986:333-337<\/p>\n

\u00a0<\/strong><\/p>\n

Ando W, Yokomori H, Isomoto A, Tachibana H, Tsutsui N, Inagaki Y, Isao Okazaki, Komiyama T. Serum apelin-36 level is useful for early detection of liver fibrosis in nonalcoholic steatohepatitis patients. Kitasato Med J. 2017;47(2):129-140<\/p>\n

 <\/p>\n

Ando W, Fukunaga, Y, Yokomori H, Komiyama T. Reduced telaprevir dosing in combination therapy for patients with chronic hepatitis C. Kitasato Med J. 2017;47(1):1-9<\/p>\n

\u00a0<\/strong><\/p>\n

2016<\/strong><\/h1>\n

 <\/p>\n

\u9752\u6728\u5b66\u4e00, \u7b2c5\u56de\u3000\u7c21\u6613\u61f8\u6fc1\u6cd5\u7814\u7a76\u4f1a\u3000\u5b9f\u6280\u30bb\u30df\u30ca\u30fc in \u6771\u4eac\u306b\u53c2\u52a0\u3057\u3066, \u7c21\u6613\u61f8\u6fc1\u6cd5\u7814\u7a76\u4f1a\u4f1a\u8a8c. 2016;4(2): 21<\/p>\n

 <\/p>\n

\u9752\u6728\u5b66\u4e00\uff0c\u6238\u6839\u5948\u6d25\u5b50\uff0c\u91d1\u6fa4\u6e29\u5b50\uff0c\u6e80\u6728\u7531\u5e03\u83dc\uff0c\u5409\u7530\u6dbc\u5e73\uff0c\u6e0b\u8c37 \u6e05\uff0c\u4e45\u4fdd\u7530\u7406\u6075\uff0c\u9152\u5411\u5b6b\u5e02\uff0c\u5c0f\u5bae\u5c71\u8cb4\u5b50. \u98db\u6563\u3057\u305f\u30ed\u30a4\u30b1\u30ea\u30f3\u00ae<\/sup>\u656310%\u306e\u74b0\u5883\u66dd\u9732\u306b\u914d\u616e\u3057\u305f\u6e05\u6383\u51e6\u7406\u6cd5\uff0d\u8abf\u5264\u73fe\u5834\u3067\u306e\u5b9f\u65bd\u4f8b\uff0d. \u65e5\u672c\u75c5\u9662\u85ac\u5264\u5e2b\u4f1a\u96d1\u8a8c<\/em>. 2016;52(3):287-291.<\/p>\n

 <\/p>\n

\u7530\u4e2d\u5eb8\u4e00. \u30a2\u30b8\u30a2\u4eba\u306b\u7279\u5fb4\u7684\u306a\u30c1\u30aa\u30d7\u30ea\u30f3\u611f\u53d7\u6027\u8981\u56e0\uff1aNUDT15\u591a\u578b. \u30d5\u30a1\u30eb\u30de\u30b7\u30a2. 2016; 52(12):1161.<\/p>\n

 <\/p>\n

\u7530\u4e2d\u5eb8\u4e00. \u767d\u8840\u75c5\u6cbb\u7642\u306b\u304a\u3051\u308bpharmacogenomics. \u81e8\u5e8a\u8840\u6db2<\/em>. 2016; 57(7):910-918.<\/p>\n

 <\/p>\n

\u6df1\u5c3e\u5927\u8f14\uff0c\u6ff1\u7551\u5553\u609f\uff0c\u9ad8\u6a4b\u4fca\u6075\uff0c\u53e4\u5bae\u3000\u572d\uff0c\u4e95\u4e0a\u7f8e\u4fdd\u5b50\uff0c\u539f\u3000\u8302\u767b\uff0c\u5118\u7530\u5149\u548c\uff0c\u5409\u7530\u3000\u6643\uff0c\u767e\u4e95\u3000\u4ea8\uff0c\u7530\u4e2d\u5eb8\u4e00. T\u7d30\u80de\u6027\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u306b\u5bfe\u3059\u308b\u7dad\u6301\u7642\u6cd5\u4e2d\u306b6-\u30e1\u30eb\u30ab\u30d7\u30c8\u30d7\u30ea\u30f3\u306b\u3088\u308b\u8457\u660e\u306a\u9aa8\u9ac4\u6291\u5236\u3092\u304d\u305f\u3057NUDT15 \u5909\u7570\u3092\u8a8d\u3081\u305f1 \u4f8b. \u65e5\u672c\u5c0f\u5150\u8840\u6db2\u30fb\u304c\u3093\u5b66\u4f1a\u96d1\u8a8c<\/em>. 2016; 53(2):139-142.<\/p>\n

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\u6728\u6751\u4fca\u4ecb\uff0c\u9577\u8c37\u5ddd\u5927\u8f14\uff0c\u5409\u672c\u512a\u91cc\uff0c\u5e73\u6797\u771f\u4ecb\uff0c\u7d30\u8c37\u8981\u4ecb\uff0c\u5409\u539f\u5b8f\u6a39\uff0c\u718a\u672c\u5fe0\u53f2\uff0c\u7530\u4e2d\u5eb8\u4e00\uff0c\u771f\u90e8\u3000\u6df3<\/p>\n

\u30e1\u30eb\u30ab\u30d7\u30c8\u30d7\u30ea\u30f3\u306b\u3088\u308b\u91cd\u5ea6\u306e\u8840\u6db2\u6bd2\u6027\u3092\u304d\u305f\u3057\u305fNUDT15\u30db\u30e2\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6709\u3059\u308b\u5c0f\u5150\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5. \u81e8\u5e8a\u8840\u6db2<\/em>. 2016; 57(6):748-753.<\/p>\n

 <\/p>\n

Tanaka Y, Tamura Y, Yokomori H, Komiyama T. Rapidity and Severity of Hemoglobin Decreasing Associated with Erythrocyte Inosine Triphosphatase Activity and ATP Concentration during Chronic Hepatitis C Treatment. BIOL PHARM BULL<\/em>. 2016; 39(4):615-619.<\/p>\n

 <\/p>\n

Okazaki I, Ishikawa S, Ando W, Sohara Y. Lung adenocarcinoma in never smokers: Problems of primary prevention from aspects of susceptible genes and carcinogens. Anticancer Research. <\/em>2016; 36(12):6207-6224.<\/p>\n

\u00a0<\/em><\/p>\n

Yokomori H, Inagaki Y, Ando W, Hara M, Komiyama T, Kojima S, Oda M, Kuroda H, Suzuki Y, Okazaki I. Spatiotemporal expression of matrix metalloproteinase-1 in progression of nonalcoholic steatohepatitis. Journal of Modern Human Pathology. <\/em>2016; 1(2):11\u201320.<\/p>\n

 <\/p>\n

2015<\/strong><\/h1>\n

\u6b4c\u91ce\u667a\u4e4b\uff0c\u7530\u4e2d\u5eb8\u4e00\uff0c\u6728\u6d25\u7d14\u5b50\uff0c\u795e\u8c37\u5c1a\u5b8f\uff0c\u5c0f\u5ddd\u5343\u767b\u4e16\uff0c\u77f3\u7530\u4e5f\u5bf8\u5fd7\uff0c\u7d30\u8c37\u4eae\u592a\uff0c\u771f\u90e8\u3000\u6df3. \u5c0f\u5150\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u306e\u7dad\u6301\u7642\u6cd5\u671f\u9593\u306b\u304a\u3051\u308b\u30e1\u30eb\u30ab\u30d7\u30c8\u30d7\u30ea\u30f3 \u53ca\u3073\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u6295\u4e0e\u91cf\u306e\u63a8\u79fb\uff5e\u5358\u65bd\u8a2d\u306b\u304a\u3051\u308b\u691c\u8a0e\uff5e. \u5c0f\u5150\u8840\u6db2\u30fb\u304c\u3093\u5b66\u4f1a\u96d1\u8a8c<\/em>. 2015; 52(5): 399-404.<\/p>\n

 <\/p>\n

\u7530\u4e2d\u5eb8\u4e00. Introduce My Article. \u81e8\u5e8a\u8840\u6db2<\/em>. 2015; 56(11): 2358.<\/p>\n

 <\/p>\n

\u5869\u898b\u3081\u3050\u307f. GLP-1 \u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u4f7f\u3044\u5206\u3051\u306b\u3064\u3044\u3066. CDEJ News Letter<\/em>. 2015; 48:12<\/p>\n

 <\/p>\n

Tanaka Y, Kato M, Hasegawa D, Urayama KY, Nakadate H, Kondoh K, Nakamura K, Koh K, Komiyama T, Manabe A. Susceptibility to 6-MP toxicity conferred by a NUDT15 variant in Japanese children with acute lymphoblastic leukaemia. British journal of haematology<\/em>. 2015; 171(1):109-115.<\/p>\n

 <\/p>\n

Tanaka Y, Manabe A, Fukushima H, Suzuki R, Nakadate H, Kondoh K, Nakamura K, Koh K, Fukushima T, Tsuchida M, Koike K, Kiyokawa N, Noguchi E, Sumazaki R, Komiyama T. Multidrug resistance protein 4 (MRP4) polymorphisms impact the 6-mercaptopurine dose tolerance during maintenance therapy in Japanese childhood acute lymphoblastic leukemia. Pharmacogenomics Journal<\/em>. 2015; 15(4):380-384.<\/p>\n

 <\/p>\n

\u7530\u4e2d\u5eb8\u4e00. Introduce My Article. \u81e8\u5e8a\u8840\u6db2<\/em>. 2015; 56(1): 51.<\/p>\n

 <\/p>\n

Yokomori H, Ando W, Yoshimura K, Yamazaki H, Takahashi Y, Oda M. Increases in endothelial caveolin-1 and cavins correlate with cirrhosis progression. Micron<\/em>. 2015; 76:52-61.<\/p>\n

 <\/p>\n

2014<\/strong><\/h1>\n

\u5c3e\u9ce5\u52dd\u4e5f\uff0c\u732a\u8170\u6df3\u55e3\uff0c\u77e2\u5f8c\u548c\u592b\uff0c\u4f9b\u7530\u6d0b: \u9759\u6ce8\u7528\u4eba\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u88fd\u5264\u306e\u54c1\u8cea\u6bd4\u8f03\u8a66\u9a13. \u533b\u7642\u85ac\u5b66<\/em>. 2014;40(8):433-440.<\/p>\n

 <\/p>\n

Tanaka Y, Manabe A, Nakadate H, Kondoh K, Nakamura K, Koh K, Kikuchi A, Komiyama T. Methylenetetrahydrofolate reductase gene haplotypes affect toxicity during maintenance therapy for childhood acute lymphoblastic leukemia in Japanese patients. Leukemia and Lymphoma<\/em>. 2014; 55(5):1126-1131.<\/p>\n

 <\/p>\n

Iguchi H, Oda M, Yamazaki H, Yoshimura K, Ando W, Yokomori H. Aquaporin-1 is associated with arterial capillary proliferation and hepatic sinusoidal transformation contributing to portal hypertension in primary biliary cirrhosis. Med Mol Morphol<\/em>. 2014; 47(2):90-9.<\/p>\n

 <\/p>\n

2013<\/strong><\/h1>\n

Kubota R, Komiyama T, Miwa Y, Bun S, Ishii J, Minei S, Irie A. Pharmacokinetics of Ketamine and Norketamine After Oral Administration of a Liquid Formulation of Ketamine. J Curr Surg. 2013;3(2):82-86<\/p>\n

\u00a0<\/strong><\/p>\n

2012<\/strong><\/h1>\n

Tanaka Y, Manabe A, Nakadate H, Kondoh K, Nakamura K, Koh K, Utano T, Kikuchi A, Komiyama T. The activity of the inosine triphosphate pyrophosphatase affects toxicity of 6-mercaptopurine during maintenance therapy for acute lymphoblastic leukemia in Japanese children. Leukemia Research<\/em>. 2012; 36(5):560-564.<\/p>\n","protected":false},"excerpt":{"rendered":"

2021 Megumi Shiomi, Momoka Kurobuchi, Yoichi Tanaka, Tesshu Takada, Katsuya Otori.\u00a0Pill Counting in the Determ…<\/p>\n","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-85","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wp.pharm.kitasato-u.ac.jp\/yakubutsu4\/wp-json\/wp\/v2\/pages\/85","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.pharm.kitasato-u.ac.jp\/yakubutsu4\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.pharm.kitasato-u.ac.jp\/yakubutsu4\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.pharm.kitasato-u.ac.jp\/yakubutsu4\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.pharm.kitasato-u.ac.jp\/yakubutsu4\/wp-json\/wp\/v2\/comments?post=85"}],"version-history":[{"count":2,"href":"https:\/\/wp.pharm.kitasato-u.ac.jp\/yakubutsu4\/wp-json\/wp\/v2\/pages\/85\/revisions"}],"predecessor-version":[{"id":88,"href":"https:\/\/wp.pharm.kitasato-u.ac.jp\/yakubutsu4\/wp-json\/wp\/v2\/pages\/85\/revisions\/88"}],"wp:attachment":[{"href":"https:\/\/wp.pharm.kitasato-u.ac.jp\/yakubutsu4\/wp-json\/wp\/v2\/media?parent=85"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}